Microbiologists in laboratory

MALDI-TOF Mass Spectrometry in the Clinical Lab

Antimicrobial resistance is rising, prompting clinical laboratories to find effective solutions for fast, accurate microorganism identification. MALDI-TOF mass spectrometry has emerged as a rapid, cost-efficient and clinically effective tool for identifying pathogens.1,2  

In this webinar, “The Use of MALDI-TOF in the Clinical Laboratory: Effectiveness and Challenges,” Dr. Elizabeth Palavecino shares her laboratory’s clinical experience with MALDI-TOF mass spectrometry. This discussion explores the clinical effectiveness of this technology in patient management as well as the challenges of antimicrobial susceptibility reporting. After viewing the webinar, you will be able to:

  • Describe MALDI-TOF mass spectrometry technology 
  • Plan an implementation of MALDI-TOF for microorganism identification in the clinical laboratory
  • Discuss the effectiveness of this technology in patient management
  • Explain the challenges associated with reporting and the impact of MALDI-TOF mass spectrometry on antimicrobial stewardship

Ideal for: Antimicrobial stewardship committees, laboratory directors, microbiologists

Presenter: Elizabeth Palavecino, M.D.
Dr. Elizabeth Palavecino is professor of pathology, director of clinical microbiology and co-director of the clinical and translational mass spectrometry center at Wake Forest School of Medicine. 

1Tan, KE et. al. “Prospective Evaluation of a Matrix-assisted Laser Desorption Ionization—Time of Flight Mass Spectrometry System in a Hospital Clinical Microbiology Laboratory for Identification of Bacteria and Yeasts: A Bench-by-bench Study for Assessing the Impact on Time to Identification and Cost-effectiveness. “J Clin Microbiol, 2012;50(10):3301–8.
2Cherkaoui, A et. al. "Comparison of Two Matrix-Assisted Laser Desorption Ionization—Time of Flight Mass Spectrometry Methods with Conventional Phenotypic Identification for Routine Identification of Bacteria to the Species Level.” J Clin Microbiol, 2010;48:1169–75.