Early Detection of Sepsis

Global Impact of Sepsis

Sepsis is a life-threatening organ dysfunction caused by a dysregulated immune response to infection. The occurrence of sepsis is increasing at an annual rate of 1.5%, making it a significant global healthcare concern. Sepsis has a high mortality rate, killing more individuals than prostate cancer, breast cancer and HIV/AIDS combined.2,3,4

Webinar Supporting Patient Sepsis Journeys from the Lab

Watch Dr. Tobin Efferen and Hunter Bowen’s presentation on sepsis diagnosis and management highlighting the use of standardized laboratory and clinical operations in the context of one patient’s journey from initial assessment in the Emergency Department through treatment in the Intensive Care Unit to eventual discharge.

Early Sepsis Detection

Infographic Solutions that Impact Sepsis Patient

With increasing frequency, UTIs caused by ESβL-producing Enterobacterales are seen in outpatients with no previous healthcare exposures.5 Learn more about how our MicroScan panels feature drugs recommended by IDSA* and the ECDC** to treat pyelonephritis and complicated urinary tract infections caused by ESBLs.

Sepsis pathway

Although many factors contribute to the high burden of sepsis, failure to establish a prompt and accurate diagnosis is considered to be key. The challenge is that sepsis presents perniciously and variably.
Derek C. Angus, MD, MPH


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*IDSA- Infectious Disease Society of America

**ECDC- European Centre for Disease Prevention and Control

1Faisal, M., et al. (2019). Computer-aided National Early Warning Score to predict the risk of sepsis following emergency medical admission to hospital: a model development and external validation study. Canadian Medical Association Journal, 191(14), E382–E389. https://doi.org/10.1503/cmaj.181418

2https://www.globaldata.com/store/report/severe-sepsis-and-septic-shock-epidemiology-analysis/

3Jones SL et al. “Reductions in Sepsis Mortality and Costs After Design and Implementation of a Nurse-based Early Recognition and Response Program.” Jt Comm J Qual Patient Saf, vol. 41, no. 11. 2015, pp. 483–91

4Judd WR, Stephens DM, Kennedy DA. “Clinical and Economic Impact of a Quality Improvement Initiative to Enhance Early Recognition and Treatment of Sepsis.” Ann Pharmacol, vol. 48, no. 10. 2014, pp. 1269–75

5. CDC. 2019. Antibiotic Resistance Threats in the United States; https://www.cdc.gov/drugresistance/biggest-threats.html#extend